Skip to main content

How is Obstetric Cholestasis Diagnosed?

    Diagnosing Obstetric Cholestasis

    • Pregnancy-specific reference ranges for liver function tests (LFTs) should be used.
    • Other causes of itching and of liver dysfunction should be excluded.
    • C - Postnatal resolution of pruritus and LFTs should be confirmed
    Treatment of Obstetric Cholestasis 

    There is no evidence that any specific treatment improves maternal symptoms or neonatal outcomes. All such therapies should be discussed with the individual woman with this in mind.

    Topical Emollients

    C - Topical emollients are safe but their efficacy is unknown.

    S-Adenosyl Methionine

    A - There is insufficient evidence to show whether S adenosyl methionine is effective for either control of maternal symptoms or for improving fetal outcome.

    Ursodeoxycholic acid

    A - There are insufficient data to support the widespread use of ursodeoxycholic acid (UDCA) outside of clinical trials. Women should be aware of the lack of robust data concerning improvement in pruritus, protection against stillbirth, and safety to the fetus or neonate.

    Dexamethasone

    B - Dexamethasone should not be first-line therapy for obstetric cholestasis, nor should it be used outside of a randomised controlled trial (RCT) without a thorough consultation with the woman.

    What is the Role of Vitamin K?

    C - It is reasonable to offer a daily supplement of water-soluble vitamin K to all women from diagnosis of obstetric cholestasis. If there is frank steatorrhoea or prolongation of the prothrombin time, the clinical case for the use of vitamin K is stronger.

    Comments

    Post a Comment

    Popular posts from this blog

    mass converter gram kilogram lb oz

    Mass Converter Mass, t = Mass, kg = Mass, g = Mass, mg = Mass, μg = Mass, lb = Mass, oz = Mass, US ton = With this converter, you can simultaneously convert several mass units to other mass units. Simple example: 1 kg = 1000 g Composite example: 1 kg and 10 g = 101000 mg Abbreviations for mass: t - tonne (metric ton); kg - kilogram; g - gram; mg - milligram; μg - microgram; lb, lbs - pound; oz - ounce.
    Post a Comment
    Read more

    Natural Remedies for Acid Reflux (GERD) Heartburn Remedies from your kitchen

    Image via Wikipedia Using natural acid reflux remedies and heartburn remedies provides you a way to rebalance your stomach digestion problems. Using antacids for acid reflux will create more acid imbalance in your body.  Using natural acid reflux remedies for this condition provides you a way that you can rebalance your stomach digestion problems. You will also gain the additional health benefits that these remedies provide. Because of the recent focus on vinegar , people across the nation are interested in  finding a vinegar cure for acid reflux so that they can create a vinegar cure for acid  reflux for themselves to use when acid reflux disease strikes.  The benefits that can  be realized from using vinegar on a regular basis have made many individuals interested in  the healthful properties of vinegar. You might also try some home remedies for acid reflux when they prepare their meals .   Some of these home remedies for acid reflux wi...
    1 comment
    Read more

    Bacteria and Food-Borne Illnesses

    What are foodborne illnesses? Foodborne illnesses are caused by eating food or drinking beverages contaminated with bacteria, parasites, or viruses. Harmful chemicals can also cause foodborne illnesses if they have contaminated food during harvesting or processing. Foodborne illnesses can cause symptoms that range from an upset stomach to more serious symptoms, including diarrhea, fever, vomiting, abdominal cramps, and dehydration. Most foodborne infections are undiagnosed and unreported, though the Centers for Disease Control and Prevention estimates that every year about 76 million people in the United States become ill from pathogens, or disease-causing substances, in food. Of these people, about 5,000 die. What are the causes of foodborne illnesses? Harmful bacteria are the most common cause of foodborne illnesses. Some bacteria may be present on foods when you purchase them. Raw foods are the most common source of foodborne illnesses because they are not sterile; examples inc...
    Post a Comment
    Read more